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Amphetamine is known to inhibit monoamine oxidase, whereas the power of amphetamine and its metabolites to inhibit several P450 isozymes as well as other enzymes hasn't been adequately elucidated. In vitro experiments with human microsomes indicate slight inhibition of CYP2D6 by amphetamine and minor inhibition of CYP1A2, 2D6, and 3A4 by one or mor

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